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Distinct phospho-forms of cortactin differentially regulate actin polymerization and focal adhesions
Cortactin is an actin-binding protein that is overexpressed in many cancers and is a substrate for both tyrosine and serine/threonine kinases. Tyrosine phosphorylation of cortactin has been observed to increase cell motility and invasion in vivo, although it has been reported to have both positive a...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , |
|---|---|
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
American Physiological Society
2008
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2584996/ https://ncbi.nlm.nih.gov/pubmed/18768925 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00238.2008 |
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