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Akt inhibition synergizes with polycomb repressive complex 2 inhibition in the treatment of multiple myeloma
Polycomb repressive complex 2 (PRC2) components, EZH2 and its homolog EZH1, and PI3K/Akt signaling pathway are focal points as therapeutic targets for multiple myeloma. However, the exact crosstalk between their downstream targets remains unclear. We herein elucidated some epigenetic interactions fo...
Zapisane w:
| Wydane w: | Cancer Sci |
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| Główni autorzy: | , , , , , , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
John Wiley and Sons Inc.
2019
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6890440/ https://ncbi.nlm.nih.gov/pubmed/31571328 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.14207 |
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