The TIF1β-HP1 System Maintains Transcriptional Integrity of Hematopoietic Stem Cells

TIF1β is a transcriptional corepressor that recruits repressive chromatin modifiers to target genes. Its biological function and physiological targets in somatic stem cells remain largely unknown. Here, we show that TIF1β is essential for the maintenance of hematopoietic stem cells (HSCs). Deletion...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Miyagi, Satoru, Koide, Shuhei, Saraya, Atsunori, Wendt, George R., Oshima, Motohiko, Konuma, Takaaki, Yamazaki, Satoshi, Mochizuki-Kashio, Makiko, Nakajima-Takagi, Yaeko, Wang, Changshan, Chiba, Tetsuhiro, Kitabayashi, Issay, Nakauchi, Hiromitsu, Iwama, Atsushi
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Elsevier 2014
Gaiak:
Report
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3923190/
https://ncbi.nlm.nih.gov/pubmed/24527388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2013.12.008
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak