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RRM but not the Asp/Glu domain of hnRNP C(1)/C(2) is required for splicing regulation of Ron exon 11 pre-mRNA

The Ron proto-oncogene is a human receptor for macrophage-stimulating protein (MSP). The exclusion of exon 11 in alternative splicing generates ΔRON protein that is constitutively activated. Heterogenous ribonucleaoprotein (hnRNP) C(1)/C(2) is one of the most abundant proteins in cells. In this manu...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:BMB Rep
Hauptverfasser: Moon, Heegyum, Jang, Ha Na, Liu, Yongchao, Choi, Namjeong, Oh, Jagyeong, Ha, Jiyeon, Kim, Hyeon Ho, Zheng, Xuexiu, Shen, Haihong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Korean Society for Biochemistry and Molecular Biology 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6889891/
https://ncbi.nlm.nih.gov/pubmed/31401978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5483/BMBRep.2019.52.11.080
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