Insights into lipid accumulation in skeletal muscle in dysferlin-deficient mice

Loss of dysferlin (DYSF) protein in humans results in limb-girdle muscular dystrophy 2B, characterized by progressive loss of muscles in the distal limbs with impaired locomotion. The DYSF-null (Bla/J) mouse develops severe steatotic muscles upon aging. Here, we report a marked increase in adipocyte...

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Udgivet i:J Lipid Res
Main Authors: Agarwal, Anil K., Tunison, Katie, Mitsche, Matthew A., McDonald, Jeffrey G., Garg, Abhimanyu
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Biochemistry and Molecular Biology 2019
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6889719/
https://ncbi.nlm.nih.gov/pubmed/31653658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.RA119000399
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