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Genetic Manipulation of Dysferlin Expression in Skeletal Muscle : Novel Insights into Muscular Dystrophy
Mutations in the gene DYSF, which codes for the protein dysferlin, underlie Miyoshi myopathy and limb-girdle muscular dystrophy 2B in humans and produce a slowly progressing skeletal muscle degenerative disease in mice. Dysferlin is a Ca(2+)-sensing, regulatory protein that is involved in membrane r...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Investigative Pathology
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2774048/ https://ncbi.nlm.nih.gov/pubmed/19834057 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.090107 |
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