STING signaling remodels the tumor microenvironment by antagonizing myeloid-derived suppressor cell expansion

Stimulator of interferon genes (STING), a major adaptor protein in antiviral innate immune signaling, is considered as one of the most important regulators of antiviral and antitumor immunity. Although STING agonists are now intensively studied in clinical trials as a new class of adjuvants to boost...

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Pubblicato in:Cell Death Differ
Autori principali: Zhang, Chuan-xia, Ye, Shu-biao, Ni, Jian-jiao, Cai, Ting-ting, Liu, Yi-na, Huang, Dai-jia, Mai, Hai-qiang, Chen, Qiu-yan, He, Jia, Zhang, Xiao-shi, Zeng, Yi-xin, Li, Jiang, Cui, Jun
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6889506/
https://ncbi.nlm.nih.gov/pubmed/30816302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-019-0302-0
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