Tumour YAP1 and PTEN expression correlates with tumour‐associated myeloid suppressor cell expansion and reduced survival in colorectal cancer

The expansion of myeloid‐derived suppressor cells (MDSCs) correlates with tumorigenesis in colorectal cancer (CRC). Here, we found a significant association between CD33(+) MDSC number and Yes‐associated protein 1 (YAP1) and phosphatase and tensin homologue (PTEN) levels in CRC patients (P < 0·05...

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Veröffentlicht in:Immunology
Hauptverfasser: Yang, Rong, Cai, Ting‐ting, Wu, Xiao‐jun, Liu, Yi‐na, He, Jia, Zhang, Xiao‐shi, Ma, Gang, Li, Jiang
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2018
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6142285/
https://ncbi.nlm.nih.gov/pubmed/29770434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12949
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