STING signaling remodels the tumor microenvironment by antagonizing myeloid-derived suppressor cell expansion

Stimulator of interferon genes (STING), a major adaptor protein in antiviral innate immune signaling, is considered as one of the most important regulators of antiviral and antitumor immunity. Although STING agonists are now intensively studied in clinical trials as a new class of adjuvants to boost...

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Vydáno v:Cell Death Differ
Hlavní autoři: Zhang, Chuan-xia, Ye, Shu-biao, Ni, Jian-jiao, Cai, Ting-ting, Liu, Yi-na, Huang, Dai-jia, Mai, Hai-qiang, Chen, Qiu-yan, He, Jia, Zhang, Xiao-shi, Zeng, Yi-xin, Li, Jiang, Cui, Jun
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6889506/
https://ncbi.nlm.nih.gov/pubmed/30816302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-019-0302-0
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