Galectin-9 promotes a suppressive microenvironment in human cancer by enhancing STING degradation

Galectin-9 (Gal-9) is known to enhance the expansion of myeloid-derived suppressor cells (MDSCs) in murine models. Its contribution to the expansion of MDSCs in human malignancies remain to be investigated. We here report that Gal-9 expression in nasopharyngeal carcinoma (NPC) cells enhances the gen...

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Detalhes bibliográficos
Publicado no:Oncogenesis
Main Authors: Zhang, Chuan-xia, Huang, Dai-jia, Baloche, Valentin, Zhang, Lin, Xu, Jing-xiao, Li, Bo-wen, Zhao, Xin-rui, He, Jia, Mai, Hai-qiang, Chen, Qiu-yan, Zhang, Xiao-shi, Busson, Pierre, Cui, Jun, Li, Jiang
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7338349/
https://ncbi.nlm.nih.gov/pubmed/32632113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41389-020-00248-0
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