Impact of depth of response on survival in patients treated with cobimetinib ± vemurafenib: pooled analysis of BRIM-2, BRIM-3, BRIM-7 and coBRIM

BACKGROUND: This pooled analysis investigated the prognostic value of depth of response in two cohorts of patients with BRAF(V600)-mutated metastatic melanoma treated with vemurafenib or cobimetinib plus vemurafenib. METHODS: The data were pooled from BRIM-2, BRIM-3, BRIM-7 and coBRIM. Association o...

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發表在:Br J Cancer
Main Authors: Lewis, Karl D., Larkin, James, Ribas, Antoni, Flaherty, Keith T., McArthur, Grant A., Ascierto, Paolo A., Dréno, Brigitte, Yan, Yibing, Wongchenko, Matthew, McKenna, Edward, Zhu, Qian, Mun, Yong, Hauschild, Axel
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2019
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6889491/
https://ncbi.nlm.nih.gov/pubmed/31417188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-019-0546-y
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