Clinical features of serous retinopathy observed with cobimetinib in patients with BRAF-mutated melanoma treated in the randomized coBRIM study

BACKGROUND: Serous chorioretinopathy has been associated with MEK inhibitors, including cobimetinib. We describe the clinical features of serous retinopathy observed with cobimetinib in patients with BRAF (V600)-mutated melanoma treated in the Phase III coBRIM study. METHODS: In the coBRIM study, 49...

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Detalhes bibliográficos
Publicado no:J Transl Med
Main Authors: de la Cruz-Merino, Luis, Di Guardo, Lorenza, Grob, Jean-Jacques, Venosa, Alfredo, Larkin, James, McArthur, Grant A., Ribas, Antoni, Ascierto, Paolo A., Evans, Jeffrey T. R., Gomez-Escobar, Antonio, Barteselli, Giulio, Eng, Susan, Hsu, Jessie J., Uyei, Anne, Dréno, Brigitte
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5483259/
https://ncbi.nlm.nih.gov/pubmed/28646893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-017-1246-0
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