Therapeutic resistance and susceptibility is shaped by cooperative multi-compartment tumor adaptation

Emerging research suggests that multiple tumor compartments can influence treatment responsiveness and relapse, yet the search for therapeutic resistance mechanisms remains largely focused on acquired genomic alterations in cancer cells. Here we show how treatment-induced changes occur in multiple t...

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Detalhes bibliográficos
Publicado no:Cell Death Differ
Principais autores: Long, Jason E., Wongchenko, Matthew J., Nickles, Dorothee, Chung, Wei-Jen, Wang, Bu-er, Riegler, Johannes, Li, Ji, Li, Qingling, Sandoval, Wendy, Eastham-Anderson, Jeff, Modrusan, Zora, Junttila, Teemu, Carano, Richard A. D., Foreman, Oded, Yan, Yibing, Junttila, Melissa R.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6889278/
https://ncbi.nlm.nih.gov/pubmed/30824837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-019-0310-0
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