IL-12 abrogates calcineurin-dependent immune evasion during leukemia progression

Exploitation of the immune system has emerged as an important therapeutic strategy for acute lymphoblastic leukemia (ALL). However, the mechanisms of immune evasion during leukemia progression remain poorly understood. We sought to understand the role of calcineurin in ALL and observed that depletio...

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Détails bibliographiques
Publié dans:Cancer Res
Auteurs principaux: Rabe, Jennifer L., Gardner, Lori, Hunter, Rae, Fonseca, Jairo A., Dougan, Jodi, Gearheart, Christy M., Leibowitz, Michael S., Lee-Miller, Cathy, Baturin, Dmitry, Fosmire, Susan P., Zelasko, Susan E., Jones, Courtney L., Slansky, Jill E., Rupji, Manali, Dwivedi, Bhakti, Henry, Curtis J., Porter, Christopher C.
Format: Artigo
Langue:Inglês
Publié: 2019
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6889000/
https://ncbi.nlm.nih.gov/pubmed/31142509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-18-3800
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