IL-12 abrogates calcineurin-dependent immune evasion during leukemia progression

Exploitation of the immune system has emerged as an important therapeutic strategy for acute lymphoblastic leukemia (ALL). However, the mechanisms of immune evasion during leukemia progression remain poorly understood. We sought to understand the role of calcineurin in ALL and observed that depletio...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Rabe, Jennifer L., Gardner, Lori, Hunter, Rae, Fonseca, Jairo A., Dougan, Jodi, Gearheart, Christy M., Leibowitz, Michael S., Lee-Miller, Cathy, Baturin, Dmitry, Fosmire, Susan P., Zelasko, Susan E., Jones, Courtney L., Slansky, Jill E., Rupji, Manali, Dwivedi, Bhakti, Henry, Curtis J., Porter, Christopher C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6889000/
https://ncbi.nlm.nih.gov/pubmed/31142509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-18-3800
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