Integrated genomic analyses identify WEE1 as a critical mediator of cell fate and novel therapeutic target in acute myeloid leukemia

Acute myeloid leukemia (AML) remains a therapeutic challenge despite increasing knowledge about the molecular origins of the disease, as the mechanisms of AML cell escape from chemotherapy remain poorly defined. We hypothesized that AML cells are addicted to molecular pathways in the context of chem...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Porter, Christopher C., Kim, Jihye, Fosmire, Susan, Gearheart, Christy M., van Linden, Annemie, Baturin, Dmitry, Zaberezhnyy, Vadym, Patel, Purvi R., Gao, Dexiang, Tan, Aik Choon, DeGregori, James
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3678731/
https://ncbi.nlm.nih.gov/pubmed/22289989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2011.392
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados