טוען...
Primary prostate cancer educates bone stroma through exosomal pyruvate kinase M2 to promote bone metastasis
Prostate cancer (PCa) metastasizes selectively to bone through unknown mechanisms. In the current study, we identified exosome-mediated transfer of pyruvate kinase M2 (PKM2) from PCa cells into bone marrow stromal cells (BMSCs) as a novel mechanism through which primary tumor-derived exosomes promot...
שמור ב:
| הוצא לאור ב: | J Exp Med |
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| Main Authors: | , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Rockefeller University Press
2019
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6888980/ https://ncbi.nlm.nih.gov/pubmed/31548301 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20190158 |
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