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Prostate cancer induces bone metastasis through Wnt-induced bone morphogenetic protein-dependent and independent mechanisms

Prostate cancer (PCa) is frequently accompanied by osteosclerotic (i.e., excessive bone production) bone metastases. Although bone morphogenetic proteins (BMPs) and Wnts are mediators of PCa-induced osteoblastic activity, the relation between them in PCa bone metastases is unknown. The goal of this...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Dai, Jinlu, Hall, Christopher L., Escara-Wilke, June, Mizokami, Atsushi, Keller, Jill M., Keller, Evan T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4432935/
https://ncbi.nlm.nih.gov/pubmed/18632632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-07-6541
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