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Prostate cancer induces bone metastasis through Wnt-induced bone morphogenetic protein-dependent and independent mechanisms

Prostate cancer (PCa) is frequently accompanied by osteosclerotic (i.e., excessive bone production) bone metastases. Although bone morphogenetic proteins (BMPs) and Wnts are mediators of PCa-induced osteoblastic activity, the relation between them in PCa bone metastases is unknown. The goal of this...

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Bibliographische Detailangaben
Veröffentlicht in:Cancer Res
Hauptverfasser: Dai, Jinlu, Hall, Christopher L., Escara-Wilke, June, Mizokami, Atsushi, Keller, Jill M., Keller, Evan T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4432935/
https://ncbi.nlm.nih.gov/pubmed/18632632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-07-6541
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