Targeting cathepsin K diminishes prostate cancer establishment and growth in murine bone

BACKGROUND: The processes of prostate cancer (PCa) invasion and metastasis are facilitated by proteolytic cascade involving multiple proteases, such as matrix metalloproteinases, serine proteases and cysteine proteases including cathepsin K (CatK). CatK is predominantly secreted by osteoclasts and s...

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Publicado en:J Cancer Res Clin Oncol
Main Authors: Liang, Weiping, Wang, Fuhao, Chen, Qiuyan, Dai, Jinlu, Escara-Wilke, June, Keller, Evan T., Zimmermann, Johann, Hong, Ni, Lu, Yi, Zhang, Jian
Formato: Artigo
Idioma:Inglês
Publicado: Springer Berlin Heidelberg 2019
Assuntos:
Original Article – Cancer Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6658578/
https://ncbi.nlm.nih.gov/pubmed/31172267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00432-019-02950-y
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