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Intratumoral delivery of RIG-I agonist SLR14 induces robust antitumor responses
Cytosolic nucleic acid–sensing pathways can be triggered to enhance immune response to cancer. In this study, we tested the antitumor activity of a unique RIG-I agonist, stem loop RNA (SLR) 14. In the immunogenic tumor models, we observed significant tumor growth delay and an extended survival in SL...
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| Publicado no: | J Exp Med |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Rockefeller University Press
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6888973/ https://ncbi.nlm.nih.gov/pubmed/31601678 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20190801 |
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