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E3 ubiquitin ligase Nedd4 is a key negative regulator for non-canonical inflammasome activation
The non-canonical inflammasome plays important roles in endotoxic shock and pyroptosis. Murine caspase-11, corresponding to human caspase-4, is centrally located in the non-canonical inflammasome pathway, which is directly activated by cytosolic lipopolysaccharide. It has been reported that ubiquiti...
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| Publicado no: | Cell Death Differ |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6888843/ https://ncbi.nlm.nih.gov/pubmed/30816303 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-019-0308-7 |
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