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E3 ubiquitin ligase Nedd4 is a key negative regulator for non-canonical inflammasome activation

The non-canonical inflammasome plays important roles in endotoxic shock and pyroptosis. Murine caspase-11, corresponding to human caspase-4, is centrally located in the non-canonical inflammasome pathway, which is directly activated by cytosolic lipopolysaccharide. It has been reported that ubiquiti...

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書目詳細資料
發表在:Cell Death Differ
Main Authors: Liu, Qingjun, Zhang, Shihui, Sun, Zhongjie, Guo, Xiao, Zhou, Hong
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2019
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6888843/
https://ncbi.nlm.nih.gov/pubmed/30816303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-019-0308-7
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