Notch-induced Asb2 expression promotes protein ubiquitination by forming non-canonical E3 ligase complexes

Notch signaling controls multiple developmental processes, thus demanding versatile functions. We have previously shown that this may be partly achieved by accelerating ubiquitin-mediated degradation of important regulators of differentiation. However, the underlying mechanism was unknown. We now fi...

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Bibliographic Details
Main Authors: Nie, Lei, Zhao, Ying, Wu, Wei, Yang, Yuan-Zheng, Wang, Hong-Cheng, Sun, Xiao-Hong
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2011
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3085721/
https://ncbi.nlm.nih.gov/pubmed/21119685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2010.165
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