Activation of WNT/Beta‐Catenin Signaling and Regulation of the Farnesoid X Receptor/Beta‐Catenin Complex After Murine Bile Duct Ligation

We have recently shown that loss of β‐catenin prevents the development of cholestatic liver injury and fibrosis after bile duct ligation (BDL) due to loss of the inhibitory farnesoid X receptor (FXR)/β‐catenin complex, which results in decreased hepatic bile acids (BAs) through activation of FXR. To...

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Dades bibliogràfiques
Publicat a:Hepatol Commun
Autors principals: Zhang, Rong, Nakao, Toshimasa, Luo, Jing, Xue, Yuhua, Cornuet, Pamela, Oertel, Michael, Kosar, Karis, Singh, Sucha, Nejak‐Bowen, Kari
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2019
Matèries:
Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6887668/
https://ncbi.nlm.nih.gov/pubmed/31832572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep4.1430
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