WNT/β-CATENIN SIGNALING PLAYS A PROTECTIVE ROLE IN THE MDR2 KO MURINE MODEL OF CHOLESTATIC LIVER DISEASE

The Wnt/β-catenin signaling pathway has a well-described role in liver pathobiology. Its suppression was recently shown to decrease bile acid (BA) synthesis, thus preventing the development of cholestatic liver injury and fibrosis after bile duct ligation (BDL). To generalize these observations, we...

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Bibliografski detalji
Izdano u:Hepatology
Glavni autori: Pradhan-Sundd, Tirthadipa, Kosar, Karis, Saggi, Harvinder, Zhang, Rong, Vats, Ravi, Cornuet, Pamela, Green, Sydney, Singh, Sucha, Zeng, Gang, Sundd, Prithu, Nejak-Bowen, Kari
Format: Artigo
Jezik:Inglês
Izdano: 2019
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7058521/
https://ncbi.nlm.nih.gov/pubmed/31489648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.30927
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