Activation of WNT/Beta‐Catenin Signaling and Regulation of the Farnesoid X Receptor/Beta‐Catenin Complex After Murine Bile Duct Ligation

We have recently shown that loss of β‐catenin prevents the development of cholestatic liver injury and fibrosis after bile duct ligation (BDL) due to loss of the inhibitory farnesoid X receptor (FXR)/β‐catenin complex, which results in decreased hepatic bile acids (BAs) through activation of FXR. To...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Hepatol Commun
Autori principali: Zhang, Rong, Nakao, Toshimasa, Luo, Jing, Xue, Yuhua, Cornuet, Pamela, Oertel, Michael, Kosar, Karis, Singh, Sucha, Nejak‐Bowen, Kari
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2019
Soggetti:
Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6887668/
https://ncbi.nlm.nih.gov/pubmed/31832572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep4.1430
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi