Activation of WNT/Beta‐Catenin Signaling and Regulation of the Farnesoid X Receptor/Beta‐Catenin Complex After Murine Bile Duct Ligation

We have recently shown that loss of β‐catenin prevents the development of cholestatic liver injury and fibrosis after bile duct ligation (BDL) due to loss of the inhibitory farnesoid X receptor (FXR)/β‐catenin complex, which results in decreased hepatic bile acids (BAs) through activation of FXR. To...

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Bibliografiske detaljer
Udgivet i:Hepatol Commun
Main Authors: Zhang, Rong, Nakao, Toshimasa, Luo, Jing, Xue, Yuhua, Cornuet, Pamela, Oertel, Michael, Kosar, Karis, Singh, Sucha, Nejak‐Bowen, Kari
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2019
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Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6887668/
https://ncbi.nlm.nih.gov/pubmed/31832572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep4.1430
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