Activation of WNT/Beta‐Catenin Signaling and Regulation of the Farnesoid X Receptor/Beta‐Catenin Complex After Murine Bile Duct Ligation

We have recently shown that loss of β‐catenin prevents the development of cholestatic liver injury and fibrosis after bile duct ligation (BDL) due to loss of the inhibitory farnesoid X receptor (FXR)/β‐catenin complex, which results in decreased hepatic bile acids (BAs) through activation of FXR. To...

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Detalhes bibliográficos
Publicado no:Hepatol Commun
Main Authors: Zhang, Rong, Nakao, Toshimasa, Luo, Jing, Xue, Yuhua, Cornuet, Pamela, Oertel, Michael, Kosar, Karis, Singh, Sucha, Nejak‐Bowen, Kari
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6887668/
https://ncbi.nlm.nih.gov/pubmed/31832572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep4.1430
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