Activation of WNT/Beta‐Catenin Signaling and Regulation of the Farnesoid X Receptor/Beta‐Catenin Complex After Murine Bile Duct Ligation

We have recently shown that loss of β‐catenin prevents the development of cholestatic liver injury and fibrosis after bile duct ligation (BDL) due to loss of the inhibitory farnesoid X receptor (FXR)/β‐catenin complex, which results in decreased hepatic bile acids (BAs) through activation of FXR. To...

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Bibliographische Detailangaben
Veröffentlicht in:Hepatol Commun
Hauptverfasser: Zhang, Rong, Nakao, Toshimasa, Luo, Jing, Xue, Yuhua, Cornuet, Pamela, Oertel, Michael, Kosar, Karis, Singh, Sucha, Nejak‐Bowen, Kari
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2019
Schlagworte:
Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6887668/
https://ncbi.nlm.nih.gov/pubmed/31832572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep4.1430
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