β-CATENIN REGULATION OF FARNESOID X RECEPTOR SIGNALING AND BILE ACID METABOLISM DURING MURINE CHOLESTASIS

Cholestatic liver diseases result from impaired bile flow and are characterized by inflammation, atypical ductular proliferation (ADP), and fibrosis. The Wnt/β-catenin pathway plays a role in bile duct development, yet its role in cholestatic injury remains indeterminate. Liver-specific β-catenin kn...

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Detalhes bibliográficos
Publicado no:Hepatology
Main Authors: Thompson, Michael D., Moghe, Akshata, Cornuet, Pamela, Marino, Rebecca, Tian, Jianmin, Wang, Pengcheng, Ma, Xiaochao, Abrams, Marc, Locker, Joseph, Monga, Satdarshan P. S., Nejak-Bowen, Kari
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5771988/
https://ncbi.nlm.nih.gov/pubmed/28714273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.29371
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