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Co-occurrence of analogous enzymes determines evolution of a novel (βα)(8)-isomerase sub-family after non-conserved mutations in flexible loop
We investigate the evolution of co-occurring analogous enzymes involved in l-tryptophan and l-histidine biosynthesis in Actinobacteria. Phylogenetic analysis of trpF homologues, a missing gene in certain clades of this lineage whose absence is complemented by a dual-substrate HisA homologue, termed...
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| Publicado no: | Biochem J |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6886522/ https://ncbi.nlm.nih.gov/pubmed/26929404 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20151271 |
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