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Identification and analysis of residues contained on β → α loops of the dual-substrate (βα)(8) phosphoribosyl isomerase A specific for its phosphoribosyl anthranilate isomerase activity

A good model to experimentally explore evolutionary hypothesis related to enzyme function is the ancient-like dual-substrate (βα)(8) phosphoribosyl isomerase A (PriA), which takes part in both histidine and tryptophan biosynthesis in Streptomyces coelicolor and related organisms. In this study, we d...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Noda-García, Lianet, Camacho-Zarco, Aldo R, Verdel-Aranda, Karina, Wright, Helena, Soberón, Xavier, Fülöp, Vilmos, Barona-Gómez, Francisco
Format: Artigo
Sprache:Inglês
Veröffentlicht: Wiley Subscription Services, Inc., A Wiley Company 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2866278/
https://ncbi.nlm.nih.gov/pubmed/20066665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.331
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