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DNA methyltransferase 1–mediated CpG methylation of the miR-150-5p promoter contributes to fibroblast growth factor receptor 1–driven leukemogenesis

MicroRNA-150-5p (miR-150-5p) plays a complex role in normal early hematopoietic development and is also implicated in the development of various different leukemias. We have reported previously that, in myeloid and lymphoid malignancies associated with dysregulated fibroblast growth factor receptor...

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Bibliografski detalji
Izdano u:J Biol Chem
Glavni autori: Hu, Tianxiang, Chong, Yating, Cai, Baohuan, Liu, Yun, Lu, Sumin, Cowell, John K.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6885633/
https://ncbi.nlm.nih.gov/pubmed/31628193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.010144
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