Hypermethylated LTR retrotransposon exhibits enhancer activity

Por Hu, Tianxiang, Zhu, Xingguo, Pi, Wenhu, Yu, Miao, Shi, Huidong, Tuan, Dorothy
Publicado no Epigenetics (2017)

Mutation in the FGFR1 tyrosine kinase domain or inactivation of PTEN is associated with acquired resistance to FGFR inhibitors in FGFR1-driven leukemia/lymphomas

Por Cowell, John K, Qin, Haiyan, Hu, Tianxiang, Wu, Qing, Bhole, Aaron, Ren, Mingqiang
Publicado no Int J Cancer (2017)

Long non-coding RNAs transcribed by ERV-9 LTR retrotransposon act in cis to modulate long-range LTR enhancer function

Por Hu, Tianxiang, Pi, Wenhu, Zhu, Xingguo, Yu, Miao, Ha, Hongseok, Shi, Huidong, Choi, Jeong-Hyeon, Tuan, Dorothy
Publicado no Nucleic Acids Res (2017)

The miR-17/92 cluster is involved in the molecular etiology of the SCLL syndrome driven by the BCR-FGFR1 chimeric kinase

Por Hu, Tianxiang, Chong, Yating, Qin, Haiyan, Kitamura, Eiko, Chang, Chang-Sheng, Silva, Jeane, Ren, Mingqiang, Cowell, John K
Publicado no Oncogene (2018)

FGFR1 fusion kinase regulation of MYC expression drives development of stem cell leukemia/lymphoma syndrome

Por Hu, Tianxiang, Wu, Qing, Chong, Yating, Qin, Haiyan, Poole, Candace J., van Riggelen, Jan, Ren, Mingqiang, Cowell, John K
Publicado no Leukemia (2018)

MicroRNA 339 promotes development of Stem Cell Leukemia/Lymphoma syndrome via downregulation of the BCL2L11 and BAX pro-apoptotic genes

Por Hu, Tianxiang, Chong, Yating, Lu, Sumin, Wang, Rebecca, Qin, Haiyan, Silva, Jeane, Kitamura, Eiko, Chang, Chang-Sheng, Hawthorn, LesleyAnn, Cowell, John K
Publicado no Cancer Res (2018)

Hydroxyurea differentially modulates activator and repressors of γ-globin gene in erythroblasts of responsive and non-responsive patients with sickle cell disease in correlation wi...

Por Zhu, Xingguo, Hu, Tianxiang, Ho, Meng Hsuan, Wang, Yongchao, Yu, Miao, Patel, Niren, Pi, Wenhu, Choi, Jeong-Hyeon, Xu, Hongyan, Ganapathy, Vadivel, Kutlar, Ferdane, Kutlar, Abdullah, Tuan, Dorothy
Publicado no Haematologica (2017)