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Hypermethylated LTR retrotransposon exhibits enhancer activity

LTR retrotransposons are repetitive DNA elements comprising ∼10% of the human genome. They are silenced by hypermethylation of cytosines in CpG dinucleotides and are considered parasitic DNA serving no useful function for the host genome. However, hypermethylated LTRs contain enhancer and promoter s...

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書目詳細資料
發表在:Epigenetics
Main Authors: Hu, Tianxiang, Zhu, Xingguo, Pi, Wenhu, Yu, Miao, Shi, Huidong, Tuan, Dorothy
格式: Artigo
語言:Inglês
出版: Taylor & Francis 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5406212/
https://ncbi.nlm.nih.gov/pubmed/28165867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15592294.2017.1289300
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