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The ERV-9 LTR enhancer is not blocked by the HS5 insulator and synthesizes through the HS5 site non-coding, long RNAs that regulate LTR enhancer function

A solitary long terminal repeat (LTR) of ERV-9 human endogenous retrovirus is located upstream of the HS5 site in the human β-globin locus control region and possesses unique enhancer activity in erythroid K562 cells. In cells transfected with plasmid LTR-HS5-εp-GFP, the LTR enhancer activates the G...

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Detalhes bibliográficos
Main Authors: Ling, Jianhua, Pi, Wenhu, Yu, Xiuping, Bengra, Chikh, Long, Qiaoming, Jin, Huaqian, Seyfang, Andreas, Tuan, Dorothy
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC169934/
https://ncbi.nlm.nih.gov/pubmed/12888519
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