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DNA methyltransferase 1–mediated CpG methylation of the miR-150-5p promoter contributes to fibroblast growth factor receptor 1–driven leukemogenesis

MicroRNA-150-5p (miR-150-5p) plays a complex role in normal early hematopoietic development and is also implicated in the development of various different leukemias. We have reported previously that, in myeloid and lymphoid malignancies associated with dysregulated fibroblast growth factor receptor...

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Dades bibliogràfiques
Publicat a:J Biol Chem
Autors principals: Hu, Tianxiang, Chong, Yating, Cai, Baohuan, Liu, Yun, Lu, Sumin, Cowell, John K.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6885633/
https://ncbi.nlm.nih.gov/pubmed/31628193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.010144
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