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The Effects of Clarithromycin on the Pharmacokinetics of Apixaban in Healthy Volunteers: A Single-Sequence Crossover Study
BACKGROUND: This was an open-label, phase I, nonrandomized, single-sequence, crossover study to evaluate the effect of concomitant administration of multiple doses of clarithromycin on the single-dose exposure, safety, and tolerability of apixaban in healthy subjects. METHODS: In total, 19 subjects...
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| Publicado no: | Am J Cardiovasc Drugs |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer International Publishing
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6885504/ https://ncbi.nlm.nih.gov/pubmed/31030414 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40256-019-00348-2 |
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