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Lack of Effect of Zafirlukast on the Pharmacokinetics of Azithromycin, Clarithromycin, and 14-Hydroxyclarithromycin in Healthy Volunteers

This randomized, open-label, crossover study was conducted to investigate whether the coadministration of zafirlukast would affect the pharmacokinetics of azithromycin, clarithromycin, or 14-hydroxyclarithromycin (14-OHC). Twelve healthy subjects (six males and six females) received single 500-mg do...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Garey, Kevin W., Peloquin, Charles A., Godo, Paul G., Nafziger, Anne N., Amsden, Guy W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89125/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10223928/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.43.5.1152
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