Enzyme-mimetic self-catalyzed polymerization of polypeptide helices

Enzymes provide optimal three-dimensional structures for substrate binding and the subsequent accelerated reaction. Such folding-dependent catalytic behaviors, however, are seldom mechanistically explored with reduced structural complexity. Here, we demonstrate that the α-helix, a much simpler struc...

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Publicado en:Nat Commun
Main Authors: Song, Ziyuan, Fu, Hailin, Baumgartner, Ryan, Zhu, Lingyang, Shih, Kuo-Chih, Xia, Yingchun, Zheng, Xuetao, Yin, Lichen, Chipot, Christophe, Lin, Yao, Cheng, Jianjun
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2019
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6884638/
https://ncbi.nlm.nih.gov/pubmed/31784526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13502-w
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