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Systemic siRNA Delivery to Tumors by Cell-Penetrating α-Helical Polypeptide-Based Metastable Nanoparticles
Systemic, non-viral siRNA delivery for cancer treatment is mainly achieved via condensation by cationic materials (e.g., lipids and cationic polymers), which nevertheless, suffers from poor serum stability, non-specific tissue interaction, and unsatisfactory membrane activity against efficient in vi...
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| Publicado no: | Nanoscale |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6734929/ https://ncbi.nlm.nih.gov/pubmed/30070662 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8nr03976c |
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