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A Cell-penetrating Helical Polymer For siRNA Delivery to Mammalian Cells

Cell-penetrating peptides (CPPs) are routinely used for intracellular delivery of a variety of cargo, including drugs, genes, and short interfering RNA (siRNA). Most CPPs are active only upon exposure to acidic environments inside of late endosomes, thereby facilitating the endosomal escape of inter...

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Bibliographic Details
Main Authors: Gabrielson, Nathan P, Lu, Hua, Yin, Lichen, Kim, Kyung Hoon, Cheng, Jianjun
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3412491/
https://ncbi.nlm.nih.gov/pubmed/22643866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2012.78
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