A Cell-penetrating Helical Polymer For siRNA Delivery to Mammalian Cells

Cell-penetrating peptides (CPPs) are routinely used for intracellular delivery of a variety of cargo, including drugs, genes, and short interfering RNA (siRNA). Most CPPs are active only upon exposure to acidic environments inside of late endosomes, thereby facilitating the endosomal escape of inter...

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Autors principals: Gabrielson, Nathan P, Lu, Hua, Yin, Lichen, Kim, Kyung Hoon, Cheng, Jianjun
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2012
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3412491/
https://ncbi.nlm.nih.gov/pubmed/22643866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2012.78
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