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The effect of side-chain functionality and hydrophobicity on the gene delivery capabilities of cationic helical polypeptides
The rational design of effective and safe non-viral gene vectors is largely dependent on the understanding of the structure-property relationship. We herein report the design of a new series of cationic, α-helical polypeptides with different side charged groups (amine and guanidine) and hydrophobici...
में बचाया:
| में प्रकाशित: | Biomaterials |
|---|---|
| मुख्य लेखकों: | , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2014
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4439012/ https://ncbi.nlm.nih.gov/pubmed/24439403 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2013.12.097 |
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