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Hsp110 mitigates α-synuclein pathology in vivo

Parkinson’s disease is characterized by the aggregation of the presynaptic protein α-synuclein and its deposition into pathologic Lewy bodies. While extensive research has been carried out on mediators of α-synuclein aggregation, molecular facilitators of α-synuclein disaggregation are still general...

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Podrobná bibliografie
Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Taguchi, Yumiko V., Gorenberg, Erica L., Nagy, Maria, Thrasher, Drake, Fenton, Wayne A., Volpicelli-Daley, Laura, Horwich, Arthur L., Chandra, Sreeganga S.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6883785/
https://ncbi.nlm.nih.gov/pubmed/31685606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1903268116
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