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MAPKAP kinase 2–mediated phosphorylation of HspA1L protects male germ cells from heat stress–induced apoptosis

Developing male germ cells are extremely sensitive to heat stress; consequently, anatomic and physiologic adaptations have evolved to maintain proper thermoregulation during mammalian spermatogenesis. At the cellular level, increased expression and activity of HSP70 family members occur in response...

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Publicat a:Cell Stress Chaperones
Autors principals: Williams, Patrick A., Kobilnyk, Heather E., McMillan, Emily A., Strochlic, Todd I.
Format: Artigo
Idioma:Inglês
Publicat: Springer Netherlands 2019
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6882973/
https://ncbi.nlm.nih.gov/pubmed/31642047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-019-01035-6
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