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Inhibition of HSP27 Phosphorylation by a Cell-permeant MAPKAP Kinase 2 Inhibitor

Heat shock protein 27 (HSP27) has been implicated in many intracellular signaling processes. Since the phosphorylation of HSP27 can modulate its activity, the ability to inhibit phosphorylation of HSP27 might have clinical relevance especially with regard to the treatment of fibrosis. We have develo...

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Détails bibliographiques
Auteurs principaux: Lopes, Luciana B., Flynn, Charles, Komalavilas, Padmini, Panitch, Alyssa, Brophy, Colleen M., Seal, Brandon L.
Format: Artigo
Langue:Inglês
Publié: 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2745729/
https://ncbi.nlm.nih.gov/pubmed/19289101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2009.03.056
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