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Inhibition of Mitogen Activated Protein Kinase Activated Protein Kinase II with MMI-0100 reduces intimal hyperplasia ex vivo and in vivo

Vein graft intimal hyperplasia remains the leading cause of graft failure, despite many pharmacological approaches that have failed to translate to human therapy. We investigated whether local suppression of inflammation and fibrosis with MMI-0100, a novel peptide inhibitor of Mitogen Activated Prot...

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Главные авторы: Muto, Akihito, Panitch, Alyssa, Kim, Namho, Park, Kinam, Komalavilas, Padmini, Brophy, Colleen M., Dardik, Alan
Формат: Artigo
Язык:Inglês
Опубликовано: 2011
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3268886/
https://ncbi.nlm.nih.gov/pubmed/22024359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vph.2011.07.008
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