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Stress- and mitogen-induced phosphorylation of the small heat shock protein Hsp25 by MAPKAP kinase 2 is not essential for chaperone properties and cellular thermoresistance.

Small heat shock proteins (sHsps) show a very rapid stress- and mitogen-dependent phosphorylation by MAPKAP kinase 2. Based on this observation, phosphorylation of sHsps was thought to play a key role in mediating thermoresistance immediately after heat shock, before the increased synthesis of heat...

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Publicat a:EMBO J
Autors principals: Knauf, U, Jakob, U, Engel, K, Buchner, J, Gaestel, M
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 1994
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC394778/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7905823/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1994.tb06234.x
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