Dealing with indeterminate outcomes in antimalarial drug efficacy trials: a comparison between complete case analysis, multiple imputation and inverse probability weighting

BACKGROUND: Antimalarial clinical efficacy studies for uncomplicated Plasmodium falciparum malaria frequently encounter situations in which molecular genotyping is unable to discriminate between parasitic recurrence, either new infection or recrudescence. The current WHO guideline recommends excludi...

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Veröffentlicht in:BMC Med Res Methodol
Hauptverfasser: Dahal, Prabin, Stepniewska, Kasia, Guerin, Philippe J., D’Alessandro, Umberto, Price, Ric N., Simpson, Julie A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2019
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6882216/
https://ncbi.nlm.nih.gov/pubmed/31775647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12874-019-0856-z
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