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Statistical methods to derive efficacy estimates of anti-malarials for uncomplicated Plasmodium falciparum malaria: pitfalls and challenges

The Kaplan–Meier (K–M) method is currently the preferred approach to derive an efficacy estimate from anti-malarial trial data. In this approach event times are assumed to be continuous and estimates are generated on the assumption that there is only one cause of failure. In reality, failures are ca...

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Detalhes bibliográficos
Publicado no:Malar J
Main Authors: Dahal, Prabin, Simpson, Julie A., Dorsey, Grant, Guérin, Philippe J., Price, Ric N., Stepniewska, Kasia
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5658934/
https://ncbi.nlm.nih.gov/pubmed/29073901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-017-2074-7
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