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Statistical methods to derive efficacy estimates of anti-malarials for uncomplicated Plasmodium falciparum malaria: pitfalls and challenges

The Kaplan–Meier (K–M) method is currently the preferred approach to derive an efficacy estimate from anti-malarial trial data. In this approach event times are assumed to be continuous and estimates are generated on the assumption that there is only one cause of failure. In reality, failures are ca...

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Библиографические подробности
Опубликовано в: :Malar J
Главные авторы: Dahal, Prabin, Simpson, Julie A., Dorsey, Grant, Guérin, Philippe J., Price, Ric N., Stepniewska, Kasia
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2017
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5658934/
https://ncbi.nlm.nih.gov/pubmed/29073901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-017-2074-7
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