Dealing with indeterminate outcomes in antimalarial drug efficacy trials: a comparison between complete case analysis, multiple imputation and inverse probability weighting

BACKGROUND: Antimalarial clinical efficacy studies for uncomplicated Plasmodium falciparum malaria frequently encounter situations in which molecular genotyping is unable to discriminate between parasitic recurrence, either new infection or recrudescence. The current WHO guideline recommends excludi...

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Bibliographic Details
Published in:BMC Med Res Methodol
Main Authors: Dahal, Prabin, Stepniewska, Kasia, Guerin, Philippe J., D’Alessandro, Umberto, Price, Ric N., Simpson, Julie A.
Format: Artigo
Language:Inglês
Published: BioMed Central 2019
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6882216/
https://ncbi.nlm.nih.gov/pubmed/31775647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12874-019-0856-z
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